D\u00fcnya genelinde artan antibiyotik direnci, modern t\u0131bb\u0131 zor durumda b\u0131rak\u0131rken bilim insanlar\u0131n\u0131 do\u011fadan ilham alan yenilik\u00e7i \u00e7\u00f6z\u00fcmler geli\u015ftirmeye y\u00f6nlendiriyor. \u0130stanbul Bilgi \u00dcniversitesi Genetik ve Biyom\u00fchendislik B\u00f6l\u00fcm\u00fc \u00f6\u011frencileri Ay\u015feg\u00fcl \u015eahin ve Deniz Helin Polat, mezuniyet projeleri kapsam\u0131nda T\u00dcB\u0130TAK deste\u011fiyle y\u00fcr\u00fctt\u00fckleri\u00a0\u201cPlantago Major Ekstrakt\u0131 ve Vankomisinin Osteomyelit Tedavisinde Birlikte Kullan\u0131m Potansiyelinin Ara\u015ft\u0131r\u0131lmas\u0131\u201d ba\u015fl\u0131kl\u0131 \u00e7al\u0131\u015fmalar\u0131yla sinir otu bitkisinin antibiyotik direncine kar\u015f\u0131 do\u011fal bir \u00e7\u00f6z\u00fcm olabilece\u011fini ortaya koydu.\u00a0<\/p>\n
B\u0130LG\u0130 Genetik ve Biyom\u00fchendislik B\u00f6l\u00fcm\u00fc Dr. \u00d6\u011fr. \u00dcyesi Ali Deniz Dalg\u0131\u00e7 ve Dr. \u00d6\u011fr. \u00dcyesi Sesil \u00c7\u0131nar\u00a0dan\u0131\u015fmanl\u0131\u011f\u0131nda y\u00fcr\u00fct\u00fclen ara\u015ft\u0131rmada, sinir otu bitkisinden elde edilen \u00f6z\u00fct\u00fcn, antibiyotik tedavisine destek olarak kullan\u0131lmas\u0131yla antibakteriyel etkinin art\u0131r\u0131lmas\u0131, ila\u00e7 dozunun d\u00fc\u015f\u00fcr\u00fclmesi ve uzun s\u00fcreli antibiyotik tedavisinin yan etkilerinin azalt\u0131lmas\u0131 ama\u00e7land\u0131.<\/p>\n
Ara\u015ft\u0131rma sonu\u00e7lar\u0131, sinir otunun osteomiyelit gibi tedavisi g\u00fc\u00e7 kemik enfeksiyonlar\u0131nda y\u00fcksek doz antibiyotik kullan\u0131m\u0131na olan ihtiyac\u0131 azaltt\u0131\u011f\u0131n\u0131 ve antibiyotiklere ba\u011fl\u0131 yan etkileri \u00f6nemli \u00f6l\u00e7\u00fcde d\u00fc\u015f\u00fcrd\u00fc\u011f\u00fcn\u00fc g\u00f6sterdi. Yap\u0131lan deneylerde \u00f6zellikle sinir otu \u00f6z\u00fct\u00fcn\u00fcn kemik enfeksiyonuna yol a\u00e7an bakterilerin \u00e7o\u011falmas\u0131n\u0131 neredeyse tamamen durdurdu\u011fu g\u00f6zlemlendi.<\/p>\n
Anneanne \u015fifas\u0131ndan bilimsel ke\u015fif<\/p>\n
Projeye ilham veren hik\u00e2ye, Deniz Helin Polat\u2019\u0131n Ardahan G\u00f6le\u2019de ya\u015fayan anneannesi Y\u0131ld\u0131z \u00d6zdemir\u2019in y\u0131llard\u0131r hayvanlar\u0131na uygulad\u0131\u011f\u0131 geleneksel bir tedavi y\u00f6ntemine dayan\u0131yor. Hayvanc\u0131l\u0131kla u\u011fra\u015fan \u00d6zdemir, yaralanan b\u00fcy\u00fckba\u015f hayvanlar\u0131n tedavisi i\u00e7in sinir otu bitkisini kaynat\u0131p unla kar\u0131\u015ft\u0131rarak yaralara s\u00fcr\u00fcyordu. Bu y\u00f6ntemin, yaralar\u0131n beklenenden \u00e7ok daha h\u0131zl\u0131 iyile\u015fmesini sa\u011flad\u0131\u011f\u0131n\u0131 g\u00f6zlemleyen Polat, \u201cGelenekten gelen bu deneyimin, antibiyotik direncinin artt\u0131\u011f\u0131 g\u00fcn\u00fcm\u00fczde yeni bir \u00e7\u00f6z\u00fcm olabilece\u011fini fark ettik. B\u00f6ylece hem k\u00fclt\u00fcrel mirastan ilham alarak hem de modern biyoteknolojinin sundu\u011fu imk\u00e2nlar\u0131 kullanarak daha etkili ve g\u00fcvenli bir tedavi geli\u015ftirmeyi hedefledik\u201d dedi.<\/p>\n
\u2018Do\u011fa temelli antibakteriyel \u00e7\u00f6z\u00fcmler enfeksiyon tedavisinde kullan\u0131lacak\u2019<\/p>\n
Ay\u015feg\u00fcl \u015eahin ise, \u201cAra\u015ft\u0131rmam\u0131z do\u011fal kaynaklardan elde edilen bitkisel i\u00e7eriklerle y\u00fcksek doz antibiyotik kullan\u0131m\u0131na duyulan ihtiyac\u0131n azalt\u0131labilece\u011fini g\u00f6steriyor. Do\u011fa temelli antibakteriyel \u00e7\u00f6z\u00fcmlerin gelecekte enfeksiyon hastal\u0131klar\u0131n\u0131n tedavisinde kritik bir rol oynayabilece\u011fini d\u00fc\u015f\u00fcn\u00fcyoruz\u201d diye konu\u015ftu.<\/p>\n
\u00a0<\/p>\n
\u00a0<\/p>\n
Kaynak: (BYZHA) Beyaz Haber Ajans\u0131<\/p>\n","protected":false},"excerpt":{"rendered":"
D\u00fcnya genelinde artan antibiyotik direnci, modern t\u0131bb\u0131 zor durumda b\u0131rak\u0131rken bilim insanlar\u0131n\u0131 do\u011fadan ilham alan yenilik\u00e7i \u00e7\u00f6z\u00fcmler geli\u015ftirmeye y\u00f6nlendiriyor.<\/p>\n","protected":false},"author":1,"featured_media":7640,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[3725,3181,2100],"class_list":["post-7639","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-antibakteriyel","tag-antibiyotik","tag-tedavisinde"],"_links":{"self":[{"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/7639","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/comments?post=7639"}],"version-history":[{"count":0,"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/posts\/7639\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/media\/7640"}],"wp:attachment":[{"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/media?parent=7639"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/categories?post=7639"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vansondakikahaberler.com.tr\/index.php\/wp-json\/wp\/v2\/tags?post=7639"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}